PRIMARY RESEARCH PAPERS (* joint corresponding author, 1 jointly placed authors)

  • Tsai MHC, Caswell SJ, Morris ER, Manna MC, Pennell S, Kelly G, Groom HCT, Taylor IA, Bishop KN Attenuation of reverse transcriptase facilitates SAMHD1 restriction of HIV-1 in cycling cells.Retrovirology 20:5 2023
  • D’souza AR, Buckingham AB, Salasc FE, Ingemarsdotter C, Iaconis G, Jarvis IJ, Lever AML, Groom HCT, Kenyon JC Duplex formation between the template and the nascent strand in the transcription-regulating sequences determines the site of template switching in SARS – CoV-2 2021 RNA Biol
  • Ordonez P, Bishop KN, Stoye JP, Groom HCT Analysis of SAMHD1 Restriction by Flow Cytometry in Human Myeloid U937 Cells. JoVE 2021 doi: 10.3791/62502 • Ordonez P, Kunzelmann S, Groom HCT, Yap M, Weising S, Meier C, Bishop KN, Taylor IA SAMHD1 enhances nucleoside-analogue efficacy against HIV-1 in myeloid cells 2017 Sci Rep 7:42824 Developed assays required for restriction phenotype characterisation
  • Groom HC1, Arnold LH1, Kunzelmann S, Schwefel D, Caswell SJ, Ordonez P, Mann MC, Rueschenbaum S, Goldstone DC, Pennell S, Howell SA, Stoye JP, Webb M, Taylor IA, Bishop KN Phospho-dependent Regulation of SAMHD1 Oligomerisation Couples Catalysis and Restriction 2015 PLoS Pathog 11(10):e1005194 (1 joint first authorship)
  • Schwefel D, Groom HCT, Boucherit VC, Christodoulou E, Walker PA, Stoye JP, Bishop KN & Taylor IA Structural basis of lentiviral subversion of a cellular protein degradation pathway 2014 Nature 505(7482):234-8 Associated “News and Views”, supervised technician and carried out key cellular work to validate structural data
  • Groom HCT, Warren AY, Neal DE, Bishop KN No evidence for infection of UK prostate cancer patients with XMRV, BK virus, Trichomonas vaginalis or human papilloma viruses 2012 PLoS One 7(3):e34221
  • Goldstone DC, Ennis-Adeniran V, Hedden JJ, Groom HC, Rice GI, Christodoulou E, Walker PA, Kelly G, Haire LF, Yap MW, de Carvalho LP, Stoye JP, Crow YJ, Taylor IA, Webb M HIV-1 restriction factor SAMHD1 is a deoxynucleoside triphosphate triphosphohydrolase. 2011 Nature 480(7377):379-82
  • Groom HCT, Bansal AS, Boucherit VC, Stoye JP, Bishop KN 2011 Retrovirology (Primary paper, >1 year’s work, accepted but withdrawn due to patient consent withdrawal – happy to elaborate at interview)
  • Groom HCT, Yap MW, Galão RP, Neil SJ, Bishop KN Susceptibility of xenotropic murine leukemia virus-related virus (XMRV) to retroviral restriction factors 2010 Proc Natl Acad Sci U S A 107(11):5166-71
  • Groom HCT, Boucherit VC, Makinson K, Randal E, Baptista S, Hagan S, Gow JW, Mattes FM, Breuer J, Kerr JR, Stoye JP, Bishop KN Absence of xenotropic murine leukaemia virus-related virus in UK patients with chronic fatigue syndrome 2010 Retrovirology 7:10
  • Groom HCT, Anderson EC, Dangerfield J, Lever AM Rev regulates translation of Human Immunodeficiency Virus Type-1 RNAs. 2009 J Gen Virol 90(Pt 5):1141-7
  • Gooding C, Clark F, Wollerton MC, Grellscheid SN, Groom H, Smith CW A class of human exons with predicted distant branch points revealed by analysis of AG dinucleotide exclusion zones 2006 Genome Biology 7(1):R1

  • Groom HCT Inclusive research: making science represent all individuals, Immunology News 2022
  • Groom HCT, Bishop KN The tale of xenotropic murine leukemia virus-related virus 2012 J Gen Virol 93:915-24
  • Groom HCT, Anderson EC, Lever AM, Rev: beyond nuclear export 2009 J Gen Virol 90(Pt 6):1303-18
  • Groom HCT Peer Review: fundamentals and the future Wiley Exchanges
  • Groom HCT The Breastfeeding Biochemist: Planning Pumping and Perfectionism Biochem (Lond) (2020) 42 (3): 22–28